Recombinant Alexa Fluor® 647 Anti-IL-2 Receptor alpha antibody [EPR22816-65] (ab317756) (2024)

Overview

• Product name

  Alexa Fluor® 647 Anti-IL-2 Receptor alpha antibody [EPR22816-65]
  See all IL-2 Receptor alpha primary antibodies

• Description

  Alexa Fluor® 647 Rabbit monoclonal [EPR22816-65] to IL-2 Receptor alpha

• Host species

  Rabbit

• Conjugation

  Alexa Fluor® 647. Ex: 652nm, Em: 668nm

• Tested applications

  Suitable for: Flow Cytmore details

  See Also

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• Species reactivity

  Reacts with: Mouse
  

• Immunogen

  Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.

• Positive control

  • Flow Cyt: Mouse splenocytes.

• General notes

  This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free production

  For more information see here.

  Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

  Alexa Fluor^® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor^® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor^® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor^® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

Properties

• Form

  Liquid

• Storage instructions

  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. Store In the Dark.

• Storage buffer

  pH: 7.40
  Preservative: 0.02% Sodium azide
  Constituents: 30% Glycerol (glycerin, glycerine), 1% BSA, 68% PBS

• Concentration information loading...

• Purity

  Protein A purified

• Clonality

  Monoclonal

• Clone number

  EPR22816-65

• Isotype

  IgG

Associated products

• Alternative Versions

  • Anti-IL-2 Receptor alpha antibody [EPR22816-65] (ab264557)
  • Anti-IL-2 Receptor alpha antibody [EPR22816-65] - BSA and Azide free (ab264570)

• Isotype control

  • Alexa Fluor® 647 Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab199093)

Applications

Target

• Function

  Receptor for interleukin-2.

• Involvement in disease

  Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.

• Sequence similarities

  Contains 2 Sushi (CCP/SCR) domains.

• Cellular localization

  Membrane.

• Information by UniProt

• Database links

  • Entrez Gene: 16184 Mouse
  • SwissProt: P01590 Mouse
  • Unigene: 915 Mouse

• Alternative names

  • Interleukin 2 receptor alpha chain antibody
  • CD25 antibody
  • CD25 antigen antibody

  see all

Images

Protocols

Datasheets and documents

References (0)